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J. Hefei Univ. Tech. (Nat. Sci.)

合肥工业大学学报(自然科学版)

JOURNAL OF HEFEI UNIVERSITY OF TECHNOLOGY (NATURAL SCIENCE)

Competent Authorities: Ministry of Education of the People's Republic of China

Sponsor by: Hefei University of Technology

ISSN 1000-1646, CN 34-1001/N

Structure characterization and bioavailability evaluation of chicken skin collagen peptide-zinc chelate

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鸡皮胶原蛋白多肽锌螯合物结构表征及生物利用率评价

Journal Information

J. Hefei Univ. Tech. (Nat. Sci.), Mar.2023, Vol.46 No.3: 415-418, 432

DOI: 10.3969/j.issn.1003-5060.2023.03.021

Authors

LIU Tengfei, ZOU Lifang, WU Lei, WEI Tian, GAO Yan, XIAO Guiran

(School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China)

Abstract and Keywords

Abstract: Chicken collagen peptide-zinc(CCP-Zn) was prepared. The physical and chemical properties of CCP-Zn were investigated by UV and IR spectra, and the zinc supplement effect of CCP-Zn in vivo was evaluated by Drosophila melanogaster model. The results showed that the zinc ion coordinated with the carboxyl group on the peptide amide I band, and the ability of zinc binding to peptide was 152.8 mg/g. ZnSO $ _{4} $ and CCP-Zn were added to the diet. The results showed that the addition of CCP-Zn could significantly improve the zinc level in Drosophila melanogaster compared with the addition of ZnSO $ _{4} $, which indicated that the CCP-Zn developed in this research could improve the absorption and utilization rate of zinc and had good zinc supplement effect.

Keywords: chicken skin; collagen polypeptide; structure characterization; zinc supplement; Drosophila melanogaster

作者信息

刘腾飞，邹莉芳，吴磊，韦田，高燕，肖桂然

（合肥工业大学食品与生物工程学院，安徽合肥230601）

摘要和关键词

摘要: 文章制备鸡皮胶原蛋白多肽锌螯合物(chicken collagen peptide-zinc, CCP-Zn)，通过紫外光谱、红外光谱研究CCP-Zn理化性质，并利用果蝇模型评价CCP-Zn的体内补锌效果。结果表明锌离子通过与多肽酰胺Ⅰ带上的羧基进行配位，肽锌结合能力达到152.8 mg/g。膳食添加$\mathrm{ZnSO_{4}}$、CCP-Zn，结果显示与$\mathrm{ZnSO_{4}}$添加组相比，CCP-Zn添加能显著提高果蝇体内锌水平，说明该研究开发的CCP-Zn可以提高锌的吸收利用率，具有良好的补锌效果。

关键词: 鸡皮；胶原蛋白多肽；结构表征；补锌；果蝇

Funding

安徽省科协人才托举计划资助项目（RCTJ202001）

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