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J. Hefei Univ. Tech. (Nat. Sci.)

合肥工业大学学报(自然科学版)

JOURNAL OF HEFEI UNIVERSITY OF TECHNOLOGY (NATURAL SCIENCE)

Competent Authorities: Ministry of Education of the People's Republic of China

Sponsor by: Hefei University of Technology

ISSN 1000-1646, CN 34-1001/N

Rapid detection of illegal addition of diazepam in special dietary foods for sleep

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睡眠类特膳食品中非法添加地西泮的快速检测

Journal Information

J. Hefei Univ. Tech. (Nat. Sci.), Jan.2024, Vol.47 No.1: 107-111, 136

DOI: 10.3969/j.issn.1003-5060.2024.01.016

Authors

YANG Wen, QU Wei

(School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China)

Abstract and Keywords

Abstract: In order to detect illegal addition of diazepam(DZP) in special dietary foods rapidly, a fast, simple and convenient colloidal gold strip method was established based on classical lateral flow strips (LFS) and gold nanoparticles(GNPs) labeling. The results showed that the prepared strip could complete the detection in less than ten minutes without complex pretreatment process, with good specificity and high sensitivity, and the visual detection limit could be as low as $ 10.0 \mu g/L $. This method is simple, safe and convenient, and can effectively realize the rapid detection of illegal addition of DZP in special dietary foods for sleep.

Keywords: immunochromatography; diazepam(DZP); rapid detection; special dietary foods; sleep

作者信息

杨雯，屈玮

（合肥工业大学食品与生物工程学院，安徽合肥230601）

摘要和关键词

摘要: 为快速检测特膳食品中非法添加的地西泮,文章基于经典的免疫层析侧流试纸(lateral flow strips,LFS)结合金纳米粒子(gold nanoparticles,GNPs)标记,建立一种快速、简单、方便的胶体金试纸条检测方法。结果表明:制备的试纸条能够在不到10 min的时间内完成检测,且无需复杂的预处理过程,特异性好,灵敏度高,视觉检测限可低至 $ 10.0\mu g/L $。该方法操作简单、安全便捷,可以有效地实现睡眠类特殊膳食食品中非法添加地西泮的快速检测。

关键词: 免疫层析；地西泮；快速检测；特膳食品；睡眠

Funding

国家重点研发计划资助项目（2018YFC1603606）

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