合肥工业大学校徽

合肥工业大学学报自科版

合肥工业大学学报(自然科学版)

JOURNAL OF HEFEI UNIVERSITY OF TECHNOLOGY (NATURAL SCIENCE)

主管：中华人民共和国教育部

主办：合肥工业大学

ISSN 1003-5060, CN 34-1083/N

鸡皮胶原蛋白多肽锌螯合物结构表征及生物利用率评价

Structure characterization and bioavailability evaluation of chicken skin collagen peptide-zinc chelate

期刊信息

合肥工业大学（自然科学版），2023年3月，第46卷第3期：415-418，432

DOI: 10.3969/j.issn.1003-5060.2023.03.021

作者信息

刘腾飞，邹莉芳，吴磊，韦田，高燕，肖桂然

（合肥工业大学食品与生物工程学院，安徽合肥230601）

摘要和关键词

摘要: 文章制备鸡皮胶原蛋白多肽锌螯合物(chicken collagen peptide-zinc, CCP-Zn)，通过紫外光谱、红外光谱研究CCP-Zn理化性质，并利用果蝇模型评价CCP-Zn的体内补锌效果。结果表明锌离子通过与多肽酰胺Ⅰ带上的羧基进行配位，肽锌结合能力达到152.8 mg/g。膳食添加$\mathrm{ZnSO_{4}}$、CCP-Zn，结果显示与$\mathrm{ZnSO_{4}}$添加组相比，CCP-Zn添加能显著提高果蝇体内锌水平，说明该研究开发的CCP-Zn可以提高锌的吸收利用率，具有良好的补锌效果。

关键词: 鸡皮；胶原蛋白多肽；结构表征；补锌；果蝇

Authors

LIU Tengfei, ZOU Lifang, WU Lei, WEI Tian, GAO Yan, XIAO Guiran

(School of Food and Biological Engineering, Hefei University of Technology, Hefei 230601, China)

Abstract and Keywords

Abstract: Chicken collagen peptide-zinc(CCP-Zn) was prepared. The physical and chemical properties of CCP-Zn were investigated by UV and IR spectra, and the zinc supplement effect of CCP-Zn in vivo was evaluated by Drosophila melanogaster model. The results showed that the zinc ion coordinated with the carboxyl group on the peptide amide I band, and the ability of zinc binding to peptide was 152.8 mg/g. ZnSO $ _{4} $ and CCP-Zn were added to the diet. The results showed that the addition of CCP-Zn could significantly improve the zinc level in Drosophila melanogaster compared with the addition of ZnSO $ _{4} $, which indicated that the CCP-Zn developed in this research could improve the absorption and utilization rate of zinc and had good zinc supplement effect.

Keywords: chicken skin; collagen polypeptide; structure characterization; zinc supplement; Drosophila melanogaster

基金信息

安徽省科协人才托举计划资助项目（RCTJ202001）

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